This work deconstructs the complex landscape of subiculum pyramidal cells into spatially segregated subclasses that may be observed, controlled, and interpreted in future experiments. We further show that these transcriptomically defined subclasses correspond to differential protein products and can be associated with specific projection targets. Hippocampal subfields are principally defined by cyto-, myelo-, and chemoarchitectures using ex vivo histology, typically in the coronal. In this lateral view of the human brain, the frontal lobe is at left, the occipital lobe at right, and the temporal and parietal lobes have largely been removed to reveal the hippocampus underneath. These subclasses were mapped onto abutting spatial domains, ultimately producing a complex laminar and columnar organization with heterogeneity across classical dorsal-ventral, proximal-distal, and superficial-deep axes. Hippocampus 1 Hippocampus Brain: Hippocampus The hippocampus is located in the medial temporal lobe of the brain. In this opinion article, we discuss surface-based methods that aim to explicitly. Histologically, based on the presence of three cortical layers and distinct unidirec. The human hippocampus varies considerably in its internal folding configuration, creating major challenges in interindividual alignment and parcellation into subfields. Hippocampus, anatomy, emotion processing, autonomic nervous system. Using single-cell RNA-seq, we find that the subiculum pyramidal cell population can be deconstructed into eight separable subclasses. Though it is often termed ‘subcortical,’ the hippocampus is composed of a folded ‘archicortical’ sheet contiguous with the neocortex. The sinuous arrangement of its gray and white matter, when seen in a frontal section, is suggestive of the curves of the. Anatomically the hippocampus is a limbic system structure deep in temporal lobe of the cerebrum it is crucial for the processing of long-term memory.
![hippocampus anatomy histology subiiculum hippocampus anatomy histology subiiculum](https://www.barnardhealth.us/human-brain/images/2125_2069_639-human-hippocampus.jpg)
Here, we investigated the extent and organizational principles governing pyramidal cell heterogeneity throughout the mouse subiculum. Graphic published in European Neurology 2005 53:171-178. Ammon horn of hippocampus Choroid fissure Fimbria Temporal horn of lateral ventricle Alveus of hippocampus Ambient cistern Dentate gyrus. Accumulating evidence suggests that the subiculum pyramidal cell population may actually be comprised of discrete subclasses. In the hippocampus, the classical pyramidal cell type of the subiculum acts as a primary output, conveying hippocampal signals to a diverse suite of downstream regions.